Nanocluster-based electrochemical sensing durable glucose monitors

This work will be performed in the group of Prof. Taurino, who works jointly between the Semiconductor Physics (HF) division (department of Physics and Astronomy) and the Micro and Nanosystems (MNS) division (Electrical Engineering department), in strong collaboration with the division of Quantum Solid State Physics (QSP) (department of Physics and Astronomy).
QSP core facilities will be key for the controlled synthesis of nanosized precipitates, i.e., the Ion and Molecular Beam Laboratory (for ion implantation) and the Cluster Deposition Facility (for soft landing of clusters). The atomic-scale structure of the precipitates will be characterized using the large range of techniques available within QSP, and complemented by electrochemical and compositional characterization tools in the HF and MNS divisions.
The current position exploits the capabilities and experimental facilities of Prof. Janssens and Prof. Vantomme and bridges to the field of sensors and biomedical applications (Prof. Taurino’s core expertise).
KU Leuven, established in 1425, ranks number 42 on the Times Higher Education list. Moreover, according to the Reuters ranking, it is the seventh most innovative university worldwide (number one in Europe, after six American universities).

Website unit

Project

Diabetes mellitus is a group of metabolic diseases characterized by chronic hyperglycaemia resulting from defects in insulin secretion, action or both. It is a major public health problem causing high costs for individuals and society. If left untreated, the chronic hyperglycaemia will lead to long-term damage, dysfunction and failure of various organs. During the last decades, several technologies have been developed to monitor glucose in diabetics (e.g., finger-stick blood tests and lately continuous glucose monitors). Such sensors are unpleasant, show a limited operational time window and expose patients to a high risk of infection and scarring if conceived for a real-time control.

This project aims at overcoming the above-mentioned limitations with the use of size-controlled and composition-controlled metal nanoclusters. The syntheses of nanoclusters on/underneath the electrode material are wafer-compatible and enable a fine control of particle size, composition and density. Thus, the candidate will attain fundamental insight in the interplay between structure, morphology, composition and electrochemical properties of the nanocluster-based electrodes for sensing glucose. Thanks to the unique experimental features and the implementation of a systematic experimental study, he/she will devise a novel electrode material with unrivaled electrochemical activity towards glucose in simulated interstitial fluid. The project’s goal is to break new ground in the development guidelines of glucose monitors for lifelong functional duration and high user-acceptability.

The results of this interdisciplinary research will lead to new scientific insights in the field of chemical sensing and bioengineering.

Profile

• You hold a Master's Degree in Physics, Material Science, Chemistry, Nanotechnology or Biomedical Engineering obtained with a good grade (at least a distinction)
• Prior knowledge in electrochemistry and material characterization tools (XPS, SEM, AFM) is a plus
• You are able to work independently,pay attention to experimental accuracy and precision with new concepts in a creative and critical way
• You have a hands-on attitude and area flexible team player
• You have good communication skills to report results (written and oral)
• You are very fluent in English, both spoken and written
• You are interested to work in a multi and interdisciplinary environment - physics, chemistry, engineering, medicine
• Previous experience as a research assistant or industrial expertise in the specific domain is a plus
• You are willing to write a PhD fellowship proposal for national funding

We are looking for an enthusiastic PhD candidate who shows a proactive attitude towards research in new electrochemical materials for biosensing. The candidate had the interest in working between physics and chemistry labs.

Offer

• You will be working in a dynamic and interdisciplinary work environment in both the Department of Physics and Astronomy and the NanoCentre at KU Leuven
• Participation to international conferences
• A full-time position for 1 year is offered (prolonged to four years upon positive evaluation)
• Complete information about a PhD at the KU Leuven is in the following link

Interested?

You can apply for this job by February 28th 2023 via the online application tool by providing the following documents

- A CV mentioning three reference people

- Motivation letter

- Complete transcripts of Bachelor and Master Degree

- Any certificate proving your proficiency in English

For more information please contact Prof. Irene Taurino, mail: irene.taurino@kuleuven.be or Prof. Ewald Janssens, mail: ewald.janssens@kuleuven.be or Prof. André Vantomme, mail: andre.vantomme@kuleuven.be

KU Leuven seeks to foster an environment where all talents can flourish, regardless of gender, age, cultural background, nationality or impairments. For any questions related to accessibility or support, please contact us at diversiteit.HR@kuleuven.be

KU Leuven seeks to foster an environment where all talents can flourish, regardless of gender, age, cultural background, nationality or impairments. If you have any questions relating to accessibility or support, please contact us at diversiteit.HR@kuleuven.be.