KU Leuven

Biosensors for occupational health

2024-09-16 (Europe/Brussels)
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The Laboratory for Soft Matter and Biophysics (ZMB) within the Department of Physics and Astronomy develops bioanalytical sensors for applications in medical diagnostics, environmental monitoring, and food safety. Within this project, we will team up with the Department of Electrical Engineering ESAT of KU Leuven (prof. Irene Taurino) and with the Environment and Health Unit of the KUL Faculty of Medicine (prof. Jeroen Vanoirbeek).

The predoctoral researcher will cooperate with all three research teams: The development and testing of the sensors under laboratory conditions takes place at ZMB and ESAT, the field studies with volunteering firefighters will be performed at the Health and Environment unit.
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Project

Firefighters are exposed to occupational health risks and one of them are polycyclic, aromatic hydrocarbon molecules (PAHs) released during fires. PAHs enter the human body not only along the lung but also through the skin and they are known as risk factors for developing cancer at a later age. To assess whether uptake of PAHs has taken place, we will develop a biosensor system that can detect characteristic PAH metabolites in the urine. The sensor will be designed for facile and low-cost routine measurements and the results will aid occupational physicians in following up their patients. The project is multi-faceted and the overall idea is to come up with a sensor-system solution that has a very high technological readiness level, ideally being close to serial production. 
The tasks of the predoctoral researcher will include, but are not limited to, the following aspects:
  • Design and implementation of the sensor instrument, including wireless data transmission and a graphical user interface.
  • Development and fabrication of microstructured electrode arrays by cleanroom techniques.
  • Functionalization of the microelectrodes with molecularly imprinted polymer layers for selective recognition of PAH metabolites.
  • Optimization of the electrochemical sensing parameters using voltammetry or impedance spectroscopy.
  • Taking the technical lead during the field studies with volunteering firefighters.

Profile

The project is interdisciplinary and suitable candidates hold a master diploma in one of the following disciplines:
  • Experimental physics, including applied physics and biophysics.
  • Engineering, including electrotechnical engineering, industrial engineering, chemical engineering, and bio-engineering.
  • Analytical, organic, or physical chemistry.
  • Nanoscience or microtechnology.

Offer

  • A full-time Ph.D. bursary contract for a period of 3 years (36 months) with a midterm evaluation during the second year, including a generous benefits package.
  • Working in an interdisciplinary and international, result-oriented team.
  • Becoming a specialist in using state-of-the-art cleanroom technology and in labelfree bioanalytical sensors.
  • Taking a leap forward towards a better preventive health care for occupational diseases.
  • Participating actively in national and international conferences and publishing in high-ranked scientific journals.
  • Following courses at the Arenberg Doctoral School according to your own interests and needs.

Interested?

For more information please contact Prof. dr. Patrick Wagner, tel.: +32 16 32 21 79, mail: patrickhermann.wagner@kuleuven.be or Prof. dr. Irene Taurino, tel.: +32 16 32 01 66, mail: irene.taurino@kuleuven.be.

KU Leuven strives for an inclusive, respectful and socially safe environment. We embrace diversity among individuals and groups as an asset. Open dialogue and differences in perspective are essential for an ambitious research and educational environment. In our commitment to equal opportunity, we recognize the consequences of historical inequalities. We do not accept any form of discrimination based on, but not limited to, gender identity and expression, sexual orientation, age, ethnic or national background, skin colour, religious and philosophical diversity, neurodivergence, employment disability, health, or socioeconomic status. For questions about accessibility or support offered, we are happy to assist you at this email address.

Informatie over de vacature

Functienaam
Biosensors for occupational health
Werkgever
Locatie
Oude Markt 13 Leuven, België
Gepubliceerd
2024-08-23
Uiterste sollicitatiedatum
2024-09-16 23:59 (Europe/Brussels)
2024-09-16 23:59 (CET)
Soort functie
PhD
Baan opslaan

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Over de werkgever

KU Leuven is an autonomous university. It was founded in 1425. It was born of and has grown within the Catholic tradition.

De pagina van de werkgever bekijken