The Winter laboratory at CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna, is recruiting a technical assistant to help us in our goal to develop novel strategies for the treatment of cancer.
The Project: Why are so many cancers still considered incurable? What proteins can actually be targeted by small molecules drugs? How can we determine the mechanism of action of hundreds of small-molecules in an unbiased manner to guide the innovation and characterization of next-generation anti-cancer therapeutics?
We hypothesize that a much larger fraction of the proteome is therapeutically actionable, but that we simply haven’t found the right tools to identify suitable small molecules to ultimately deliver novel medicines. The overall goal of this project is to change this paradigm. The successful applicant will work on these questions as part of a multi-disciplinary research team at CeMM in Vienna, and in close contact with our partners at Pfizer in Cambridge/US. At this vibrant interface between academia and industry, the successful candidate has a unique opportunity to achieve translational impact, pick up cutting-edge technologies and grow an expertise in proteomics. The goal of this project is to develop drugs to eliminate disease-relevant proteins via a targeted protein degradation, and thereby to innovate novel therapeutic strategies for life-threatening diseases.
The Candidate: We are seeking enthusiastic and energetic candidates to join our team. The successful applicant should have a Bachelor or Master’s degree in life sciences and an excellent background in molecular biology and biochemistry. Candidates that have a PhD degree will also be considered. The main duties include the generation, labelling and analysis of proteomics samples, including hands-on experience with handling and maintaining the latest generation of mass spectrometers. Prior experience with analytic chemistry, LC-MS or proteomics will thus be considered an advantage, but is not a prerequisite. General laboratory management and organizational skills are also part of the job requirements, including the establishment of SOPs and protocol development. We would expect the candidate to be proficient in MS Office. Advanced computer skills (R, Python) or experience with specialized proteomics analysis software tools (MaxQuant, Proteome Discoverer) are considered a plus.
The working language at CeMM is English, and excellent written and oral communication skills, as well as high accuracy, reliability and excellent interpersonal and organizational skills, are a requirement.
The Institute: CeMM is a biomedical flagship institute in the heart of Europe, Vienna. We are committed to highest scientific standards and provide an international environment representing approximately 40 nationalities. The working language is English. CeMM has been ranked by The Scientist as one of the Best Places to Work Academia worldwide (link: http://goo.gl/51VMO). In the past 3 years CeMM groups published numerous ground-breaking studies in prestigious journals such as Science, Cell, Nature, New England Journal of Medicine, Nature Immunology, Immunity etc. CeMM is located within the medical campus of Vienna and operates several technology platforms (chemical biological screening, proteomics, metabolomics, next-generation sequencing) as well as extensive bioinformatics infrastructure.
Your Application: Interested candidates are encouraged to upload their application documents (including a cover letter, a CV and names and contact details of at least 2 referees) online: https://cemm.jobbase.io/job/1eagxkog Applications will be reviewed on a rolling basis until the position is filled.Meer informatie
|Titel||Technical Assistant position in Targeted Protein Degradation and Proteomics|
|Job location||Lazarettgasse 14, AKH BT 25.3, A-1090 Vienna|
|Gepubliceerd||september 24, 2020|
|Vakgebieden||Kankeronderzoek,   Biochemie,   Analytische chemie,   Moleculaire biologie,   Celbiologie  |