Postdoctoral researcher in cancer immunotherapy (up to two positions)

Do you want to contribute to top quality medical research?

The overall aim of the Nyberg lab is to develop and use cutting-edge technologies for genetical engineering to enhance T cell therapies of cancer. As part of the Center for Hematology and Regenerative Medicine (HERM) and The Center for Cellular Cancer Therapy (C3T) at the Karolinska Institute, the lab is part of collaborative environments of excellent translational research groups. These centers encompass basic, translational, and clinical principal investigators with a focus on understanding and improving cellular immunotherapies against cancer. We offer an engaging and international research environment where you may contribute to high quality research on an internationally competitive level.

We are looking for postdoctoral researchers to work with T cell therapies and synthetic immunology to join the Nyberg lab and to contribute to the positive environment in the lab. 

Your mission

The use of chimeric antigen receptors (CAR) in T cells has transformed the field of cell therapies for cancers. We have developed cutting-edge technologies to generate precisely engineered CAR-T cells using gene targeting, and new types of adeno-associated viruses (AAV) that allow for T cell specific genetic manipulations. The current goal of the lab is to use these technologies to maximize the potential of CAR-T cell therapies. Recent development in the field has opened up the possibilites to manipulate and genetically enchance T cells in vivo (Nyberg et al., Immunity, 2025). The projects related to this position will focus on applying in vivo gene editing technologies to enhance T cell therapies of cancer.

You will be working in an international and interdisciplinary research environment, where collaborative efforts are encouraged and your development to scientific independence will be fostered.

To build a strong and creative research team, we are looking for high achievers from universities around the world. We will offer an intellectually stimulating environment with prominent guest researchers and we look for talented people who will play a part in developing our next breakthrough ideas. Our aim is to promote independent researchers that will build their careers in science.

Your profile

To be eligible for employment as a postdoctor, a PhD or a foreign degree deemed to be equivalent to a Swedish PhD is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. Completion of your doctoral degree within the last three years is considered an advantage. If there are special reasons, your degree may have been completed earlier.

You have a PhD in the field of immunology or immunotherapy of cancer and a great interest in immunotherapy.

Required skills:

• At least one first author publication in a recognized peer-reviewed journal.
• Good knowledge of immunology and immunotherapy of cancer
• Experimental knowledge of immunological methods.
• Hands on experience with animal models of cancer.
• Effective communication in English, both spoken and written.
• Excellent communication skills and capacity to work collaboratively.
• Ability to work independently and manage multiple projects in parallel.

Desirable skills:

• Hands-on experience with cell culture, cell sorting, and advanced flow cytometry.
• Hands-on experience with primary cell culture and tissue processing.
• Experience with viral vector for cell transduction.
• Experienced with molecular biology tools.
• Experience with genetical engineeing. Designing and modify CAR constructs. 

We place great importance on personal suitability.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Flemingsberg

Choose to work at KI – Ten reasons why

Center for Hematology and Regenerative Medicine (HERM)

Application

An employment application must contain the following documents in English or Swedish:

• PhD certificate
• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest 2025-05-30.

The application is to be submitted through the Varbi recruitment system.

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Want to make a difference? Join us and contribute to better health for all!

1. Balbir Dhuper, HR-partner, [email protected]
2. William Nyberg, Recruting manager, [email protected]

1. Belinda Pannagel, SACO, [email protected]
2. Mari Gilljam, OFR, [email protected]
3. Peter Svensson, SACO, [email protected]